The recent publication on unipedicular baloon kyphoplasty is very interesting [1]. It demonstrates that high seroprevalence could be seen [1]. La Maida et al. [1] found that "Both vertebroplasty and kyphoplasty are effective in treating vertebral compression fracture due to multiple myeloma." This is concordant with the biomechanical properties of the two techniques [2]. Hence, the selection of usage might be based on other factors. The interesting issue is the comparative cost between both techniques. Studying the cost effectiveness of each technique is worthwhile, and could be helpful for the selection of technique for kyphoplasty.